Somatic vs Germline Mutations

In multicellular organisms, mutations can be classed as either somatic or germ-line:

  • Somatic mutations – occur in a single body cell and cannot be inherited (only tissues derived from mutated cell are affected)
  • Germline mutations – occur in gametes and can be passed onto offspring (every cell in the entire organism will be affected)

Germline versus Somatic Mutations

somatic vs germline