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Protein Synthesis

The central dogma of molecular biology explains the flow of genetic information within a cell

  • DNA is the master set of instructions for all cell activities (i.e. the genetic ‘blueprint’ of the cell)

  • RNA (messenger RNA) is a temporary ‘photocopy' of specific genetic instruction (gene)

  • Proteins are the products created from these instructions that carry out the cellular functions

RNA → Protein

The genetic instructions of a cell encode the amino acid sequences of polypeptide chains (proteins)

  • DNA instructions can be selectively transcribed into mRNA sequences to allow for the variable expression of proteins

  • The differential expression of proteins within a cell will determine its functional activity 

The process of protein synthesis is called translation and occurs at the ribosomes

  • Proteins can be synthesised by cytosolic ribosomes or by ribosomes embedded to the rough endoplasmic reticulum

  • Cytosolic ribosomes produce intracellular proteins, while the rough ER synthesises proteins for specific organelles or extracellular use

Central Dogma
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