The central dogma of molecular biology explains the flow of genetic information within a cell
DNA is the master set of instructions for all cell activities (i.e. the genetic ‘blueprint’ of the cell)
RNA (messenger RNA) is a temporary ‘photocopy' of specific genetic instruction (gene)
Proteins are the products created from these instructions that carry out the cellular functions
RNA → Protein
The genetic instructions of a cell encode the amino acid sequences of polypeptide chains (proteins)
DNA instructions can be selectively transcribed into mRNA sequences to allow for the variable expression of proteins
The differential expression of proteins within a cell will determine its functional activity
The process of protein synthesis is called translation and occurs at the ribosomes
Proteins can be synthesised by cytosolic ribosomes or by ribosomes embedded to the rough endoplasmic reticulum
Cytosolic ribosomes produce intracellular proteins, while the rough ER synthesises proteins for specific organelles or extracellular use