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Protein Folding

Polypeptide chains are composed of 20 different types of amino acids, each with specific variable side chain

  • These side chains will have distinct chemical properties (e.g. charged, non-polar, etc.) and hence cause the protein to fold differently according to its specific position within the polypeptide chain

  • The way a protein molecule folds plays a critical role in determining its eventual function and level of biological activity

As most natural polypeptide chains contain between 50 – 2000 amino acid residues, organisms are capable of producing a huge range of possible polypeptides

  • Consequently, proteins are a very diverse class of compounds and may serve a number of different roles within a cell

Functions of Proteins
Proteins perform an array of functions:
  • Structure (collagen, spider silk)

  • Hormones (insulin, glucagon)

  • Immunity (antibodies)

  • Transport (protein channels)

  • Sensations (rhodopsin)

  • Movement (actin, myosin)

  • Enzymes (Rubisco, amylase)

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