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Hormone Signalling

The nervous system and endocrine system are linked by a section of the brain called the hypothalamus

  • The hypothalamus acts as a homeostatic control centre and regulates hormonal secretion via the pituitary gland

The pituitary gland lies adjacent to the hypothalamus and consists of two lobes (anterior and posterior lobes)

  • The hypothalamus produces releasing factors which trigger the release of certain hormones synthesised in the anterior lobe

  • The hypothalamus also produces certain hormones which are directly released from the posterior lobe (via neurosecretory cells)

Pituitary Gland
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Endocrine Signalling

The pituitary gland is often referred to as the ‘master gland’, as it controls the secretion of hormones from a number of other endocrine glands

  • Pituitary hormones will often target endocrine glands in other organs (e.g. gonads, pancreas, thyroid, mammary gland)

Examples of endocrine glands include:

  • Pancreas – Releases insulin and glucagon to regulate glucose concentrations within the bloodstream

  • Adrenal gland – Releases adrenaline (epinephrine) to stimulate 'fight or flight’ responses within the body

  • Thyroid gland – Releases thyroxin to increase metabolic activity and produce heat (for thermoregulation)

  • Gonads – Release sex hormones from either testes (testosterone) or ovaries (oestrogen and progesterone)

  • Pineal gland – Releases melatonin to regulate circadian rhythms (day-night cycles for sleeping and waking)

Endocrine Glands
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