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Cytokinesis

Cytokinesis is the process of cytoplasmic division, whereby the cell splits into two identical daughter cells

  • Cytokinesis occurs concurrently with the final stage of nuclear division (mitosis or meiosis) and is different in plant and animal cells

Animal Cells
  • After anaphase, actin and myosin filaments form a concentric ring around the centre of the cell

  • The microfilaments constrict to form a cleavage furrow, which deepens from the periphery towards the centre

  • When the furrow meets in the centre, the cell becomes completely pinched off and two cells are formed

  • Because this separation occurs from the outside and moves towards the centre, it is described as centripetal

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Plant Cells
  • After anaphase, carbohydrate-rich vesicles form in a row at the centre of the cell (equatorial plane)

  • The vesicles fuse together and an early cell plate begins to form within the middle of the cell

  • The cell plate extends outwards and fuses with the cell wall, dividing the cell into two distinct daughter cells

  • Because this separation originates in the centre and moves laterally, it is described as centrifugal

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In most cases, cytoplasmic division results in two cells of comparable sizes, with all organelles equally segregated between the daughter cells

  • Some organelles (including endoplasmic reticulum and Golgi bodies) are disassembled during nuclear division and then redistributed and reformed in daughter cells

  • Other organelles (including the mitochondria and chloroplast) undergo their own division process prior to cytokinesis to ensure the daughter cells have adequate quantities

  • Any daughter cell that does not possess a full complement of organelles will be unable to maintain the functions of life

Some cells do not partition their cytoplasm equally when they divide – instead the parent cell retains its physical identity and a new cell evolves as an outgrowth

  • This type of unequal cytokinesis can occur in both unicellular organisms (e.g. budding in yeast) and multicellular organisms (e.g. oogenesis in humans)

Budding

  • Budding is an asexual reproduction method employed by a range of organisms, including unicellular yeast

  • The division of cytoplasm is asymmetrical – the daughter cell receives only a fraction of the cytoplasm from the parent cell

  • Initially the daughter cell will remain attached to the parental cell as an outgrowth, before eventually separating and developing into an independent structure 

Oogenesis

  • Oogenesis is the process by which human egg cells (ova) are produced following meiotic division in females

  • During oogenesis, the cytoplasm and organelles are retained by a single cell, with the remainder forming a smaller polar body that will typically disintegrate

  • Retaining the cytoplasm and organelles within a single cell ensures that a fertilised ovum has sufficient resources to undergo embryonic development

Unequal Cytokinesis
Oogenesis (Human)
Budding (Yeast)