Prokaryotic vs Eukaryotic DNA

Prokaryotic DNA:

  • Is found freely in the cytoplasm (within a region called the nucleoid)
  • Is naked (i.e. not bound with proteins and therefore doesn’t form chromatin)
  • Genomes are compact (contain little repetitive DNA and no introns)
  • Contains extra-chromosomal plasmids
  • Is circular in shape

Eukaryotic DNA:

  • Is contained within a nucleus
  • Is bound to histone proteins
  • Genomes contain large amounts of non-coding and repetitive DNA (including introns)
  • Do not contain plasmids (but organelles such as the mitochondria may contain their own chromosomes)
  • Are linear in shape

Prokaryotic vs Eukaryotic DNA

pro vs eu DNA