Peptide Bonds

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•  Amino acids are linked together by condensation to form polypeptides

Amino acids can be covalently joined together in a condensation reaction to form a dipeptide and water

The covalent bond between the amino acids is called a peptide bond and, for this reason, long chains of covalently bonded amino acids are called polypeptides

Polypeptide chains can be broken down via hydrolysis reactions, which requires water to reverse the process

Formation of a Dipeptide


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•  Drawing molecular diagrams to show the formation of a peptide bond

Peptide bonds are formed between the amine and carboxylic acid groups of adjacent amino acids

  • The amine group loses a hydrogen atom (H) and the carboxylic acid loses a hydroxyl (OH) – this forms water (H2O) 

Molecular Diagram of a Peptide Bond

peptide bond